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References - Clinical Guide to the Use of Vitamin C

Page II:

  • Pauling, L.: Vitamin C and the Common Cold; W. F. Freeman & Co. San Francisco, 1970.
  • Brody, H.D.: J. Amer. Diet. Assoc., 29: 588, 1953.

Page 2, How it Works:

  • Klenner, F.R.: Virus Pneumonia and its Treatment with Vitamin C. Southern Med. Surg., Feb. 1948
  • Klenner, F.R.: Encephalitis as a Sequela of the Pneumonias. Tri-State Med. J., Feb. 1960.
  • Klenner, F.R.: An Insidious Virus. Tri-State Med J, June 1957.
  • Burns, J.J., et al: J. Biol. Chem., 207:679, 1954.
  • Salomon, L.L., Conney, A.H., et al: NY Acad Science, 92:115, 1961.
  • Burns. J.J.: Am. J. Med. 26:740, 1959.
  • Stone, I.: Brief proposal. Per. Biol Med., Autumn, 1966.

Page 1-2:

  • Arber, E: The Story of the Pilgrim Fathers, 1897.
  • Correspondence with colleague from Puerto Rico.
  • Kline, A.B. and Eheart, M.S. Variations in the Ascorbic Acid Requirements for Saturation of Nine Normal Young Women, J. Nutrition 28: 413, 1944.
  • Joliffe, N. Preventive and Therapeutic Use of Vitamins, JAMA, 129:613, 1945.
  • Crandon, J.H., Lund, C.C. and Dill, D.B.:. Experimental Human Scurvy. N Eng J Med., 223: 353, 1940.

Page 2-3:

  • Klenner, F.R.: Massive Doses of Vitamin C and the Virus Diseases. J. So. Med. & Surg., 113:#4, Apr. 1951.
  • Larson, C.: Ordinace, pp. 359-360, Jan-Feb, 1967.

Page 3:

  • Starr, T.J.: Hospital Practice, 52, Nov 1968.
  • Kropowski, H.: Med. World News, p 24, June 19,, 1970.
  • Lojkin cited in Klenner’s paper: Massive Doses of Vitamin C and the Virus Diseases.
  • McCall, C.E., and Copper, R.,: Vitamin C Shows Promise as a Bactericidal Agent. Bowman Gray School Med. Alumni News, 14:1, Feb, 1972
  • Wintrobe, M.M.: Clinical Hematology, Lea and Febiger, 3rd Ed 1952.
  • Nossal, G. Most Killed Vaccines in Use not Termed Fit for a Mouse. Medical Tribune, Apr. 5, 1972.
  • Kiegler, Guggenheim and Warburg: Vitamin C vs. Toxins, 1938. (No reference cited.)

Page 4:

  • Harde and Benjamin (1934-1935) found the Vitamin C fraction of the adrenal glands greatly reduced in monkeys killed or paralyzed by the virus of poliomyelltis.
  • Yavorsky, Almoden and King (1934) reported identical findings in humans having died of various infectious agents.

Page 4,5:

  • Klenner, F.R.: An Insidious Virus. Tri-State Med. J., June 1957
  • Klenner, F.R.: Virus Pneumonia and its Treatment with Vitamin C. Southern Med. Surg., Feb. 1948.
  • Klenner, F.R.: Encephalitis as a Sequela of the Pneumonias. Tri-State Med J., Feb, 1960
  • Gothlin, G.F.: A Method of Establishing the Vitamin C Standard of Requirement of Physically Healthy Individuals by Testing the Strength of Their Capillaries. (No reference cited.)
  • Baker, A.B. and Noran, J.A.: Changes in the Central Nervous System Associated with Encephalitis Complicating Pneumonia. Archives of Internal Med., Vol 76: 146-153, July-Dec. 1945.
  • Krumholz, S. and Luhan, J.A.: Encephalitis Associated with Herpes Zoster. Arch Neur Psych, 53: 59-67 Jan-Jun, 1945.
  • Bakay, L,: The Blood-Brain Barrier, C. C. Thomas, Pub., Springfield, IL 1956
  • Chambers, R. and Zweifach, B.W.: Intercellular Cement and Capillary Permeability, Physiol Rev., 27: 436-463, 1947.
  • Youmans, J.B.: Nutritional Deficiencies, 1941.

Page 5:

  • Hawley, E.E., Frazer, J.P., Button, L.L. and Stevens, D.J.: The Effect of the Administration of Sodium Bicarbonate and of Ammonium Chloride on the Amount of Ascorbic Acid Found In the Urine. J. Nutrition, 12:215 (August) 1936.
  • Klenner, F.R.: Significance of High Daily Intake of Ascorbic Acid in Preventive Medicine. J. Intl Acad Prev Med., 1:45-69, Spring, 1974.
  • Klenner, F.R.: Use of Vitamin C as an Antibiotic. J. of Appl Nutrit., 6: 1953 (Paper presented at AAN Convention, May, 1963, Pasadena, CA.)

Page 6, Dosage:

  • Klenner, F.R.: Massive Doses of Vitamin C and the Virus Diseases. J. So Med & Surg, 113: #4, Apr. 1951.
  • Shaw, et al: Acute and Chronic Ascorbic Deficiencies in Rhesus Monkeys. J. Nutrition, 29: 365, 1945
  • Rivers, T.M.: Immunological and Serological Phenomena in Poliomyelitis. Lecture III, Infantile Paralysis, 1941.

Page 7:

  • Klenner, F.R.: Significance of High Daily Intake. op cit.

Page 8:

  • Klenner, F.R.: Use of Vitamin C as an Antibiotic, op cit.

Page 9 Tests:

  • Klenner, F.R.: A New Office Procedure for the Determination of Plasma Levels for Ascorbic Acid. Tri-State Med J., 5, 1956.

Lingual tests:

  • Ringsdorf, W.M. & Cheraskin, E.: Sec. Oral Med., U of AL Med Center, Birmingham, AL

Page 9-16, Insidious Virus:

  • Klenner, F.R.: An Insidious Virus, op cit.
  • Klenner, F.R.: The Clinical Evaluation and Treatment of a Deadly Syndrome Caused by an Insidious Virus. Tri-State Med J., Oct. 1958.

Page 15, Virus Pneumonia:

  • Klenner, F.R.: Virus Pneumonia and its Treatment with Vitamin C. So Med & Surg, Feb. 1948.
  • Klenner, F.R.: Encephalitis as a Sequela of the Pneumonias. op cit ibid.

Page 15, (Herpes Encephalitis):

  • Lerner, M, et al: Detecting Herpes Encephalitis Earlier. Med World News, May 20, 1972.

Page 15, (X-ray Therapy):

  • Oppenheimer, A.: Roentgen Therapy of Virus Pneumonia. Amer J of Roentgen., 49: #5.

Page 17-21, Poliomyelitis:

  • Klenner, F.R.: The Treatment of Poliomyelitis and Other Virus Diseases With Vitamin C. So Med & Surg, Vol. 111: #7, July 1949.
  • Klenner, F.R., The Vitamin and Massage Treatment for Acute Poliomyelitis. So Med & Surg, 114: #8, August 1952.
  • Klenner, FR.: Poliomyelitis—Case Histories. Tri-State Med J., Sept 1956.
  • Sabin, A.B.: Vitamin C in Relation to Experimental Poliomyelitis. J Exp Med., 69: 507, 1939.
  • Heaslip, Australian J. Exp Biol. & Med., 1948.
  • Jungeblut, C.W.: Vitamin C Therapy and Prophylaxis in Experimental Poliomyelitis. J Exper Med., 65; 127, 1937.
  • Jungeblut, C.W.: Further Observations on Vitamin C Therapy in Experimental Poliomyelitis. J. Exper. Med., 66: 450, 1937.
  • Bodian, D. and Horstmann, D.:. Review of Their Work. JAMA, 149: Aug30, 1952.

Page 22-23, Hepatitis:

  • Freebern, R.K. & Repsher, LR.: Med. World News, Jan 23, 1970.
  • Klenner, F.R.: Unpublished paper.
  • Klenner, F.R.: Significance of High Daily Intake. op cit., page 56.
  • Klenner, F.R.: Massive Doses of Vitamin C, op cit.
  • Klenner, F.R.: Observations on the Dose and Administration, op cit.

Page 23-24, Herpes:

  • Klenner, F.R.: Significance, ibid, page 64.
  • Stephens, J.C. and Cook, M.: Cases of the Hidden Herpes Virus, Med World News, May 26, 1972.
  • Goodpasture, E.W.: Case of the Hidden Herpes Virus. Med World News, Feb 25, i972.
  • Roizman, B. et al: Tracing Herpes Viruses. Med World News, Oct 1, 1971.
  • Klenner, F.R.: Use of Vitamin C as an Antibiotic. op cit.

Page 24-25, Chickenpox and Measles:

  • Klenner, F.R.: Massive Doses, op cit.
  • Klenner, F.R.: The use of Vitamin C as an Antibiotic. op cit.

Page 26, Infectious Mononucleosis:

  • Hellne, C. and Helene, W.: EB Virus in the Etiology of Infectious Mononucleosis, Hosp Pract., July, 1970.
  • Niderman, College Findings tie Mono to ED virus. Med World News, Dec 1968.
  • Klenner, F.R.: Observations of the Dose and Administration. op cit.

Page 27,

  • Klenner, ER.: Unpublished work on RMSF and tick bite fever.

Page 28 Trichinosis:

  • Klenner, F.R.: The Treatment of Trichinosis with Massive Doses of Vitamin C and Para-aminobenzoic Acid. Tri-State Medical J., April i954.

Page 30, Urethritis:

  • Rous, S.: Urethritis in Men. NY Soc Med., Dec 15, 1971.

Page 30, Antabuse:

  • Klenner, F.R.: Unpublished paper.

Page 31, Arthritis:

  • Klenner, F.R.: Significance. op cit.
  • Abrams, E. and Sandson, J.: Ann Rheum Dis., 27: 1964.

Page 31, Cancer

  • Klenner, F.R.: Unpublished paper.
  • Schiegel, G.E. et al: The Role of Ascorbic Acid in the Prevention of Bladder Tumor Formation. Trans Amer Assn Genitour Surg., 61: 1969.

Page 33-34, Cholesterol and Arteriosclerosis:

  • Ginter, E.L.: Cholesterol and Vitamin C. Amer J Clin Nutr., 24: 1238-1245, 1971.
  • Spittle, C., Atherosclerosis and Vitamin C. Lancet, II: 1280-1281, 1971.
  • Ginter, E.: Effects of Dietary Cholesterol on Vitamin C Metabolism in laboratory animals. Acta Med Acad Sci. Hungary. 27:23-29; 1970.
  • Ginter, E., et al: The Effects of Ascorbic Acid on Cholesterolemia in Healthy Subjects with Seasonal Deficit of Vitamin C. Nutr Metabol, 12: 76-86. 1970.
  • Willis, G.C.: An Experimental Study of the Intimal Ground Substance in Atherosclerosis. Can Med Assoc J., 69: 17-22, 1953.
  • Shafer, J.: Ascorbic Acid and Atherosclerosis. Amer J Clin Nutr., 23:27, 1970.
  • Stamler, J.: Comprehensive Treatment of Essential Hypertensive Diseases. Monograph on Hypertension, Merck, Sharp and Dohme.
  • Hecker, R.R. et al: J Am Chem Soc., 75:2020, 1953.

Page 34, Corneal Ulcers:

  • Boyd,T.A., & Campbell, F.W.: B Med J., 2:1145, Nov 1950.

Page 35, Glaucoma:

  • Virno, M.: Eye, Ear, Nose and Throat Monthly, 46:1502.

Page 35, 36 Pregnancies:

  • Greenblatt, R.B.: Obst & Gyn, 2:530, 1953.
  • King, C.C. et al, New York Times, Nov 2, 1952.

Page 36-39, Schizophrenia, Heat Stroke, Sunburn, Slipped Disc, Toxins and Heavy Metal Poisonings:

  • Klenner, F.R.: Significance of High Daily Intake,. op cit.
  • Klenner, F.R.: The use of Vitamin C as an Antibiotic, op cit.
  • Mokranjac, M. and Petrovic, C.: Report on Mercury Studies in Guinea Pigs in Relation to Amounts of Vitamin C Administered. Cr Acad Sci., Paris.
  • Dannenburg, A.M. et al: Ascorbic acid in the treatment of chronic lead poisoning. JAMA, 114:1439-1440, 1940.
  • Pelletier, O.: Experiments with smokers and non-smokers. JAMA, April 1969.
  • Mayers, B.W.: Where there’s smoke there may be carbon monoxide. Med World News, Jan 21, 1972.
  • Hoffer, J.: Use of Ascorbic Acid with Niacin in Schizophrenia. Can Med J., Nov 6, 1971.
  • Hawkins, D.: Back to Reality the Megavitamin Way. Med World News, Sept 24, 1971.
  • Greenwood, J.: Optimum Vitamin C Intake as a Factor in the Preservation of Disc Integrity. Med Ann DC, 33:6, June 1964.
  • Massell, B.F. et al: Antirheumatic Activity of Ascorbic Acid in Large Doses. New Eng J Med, 1950.
  • Kyhos, E.D. et al: Large Doses of Ascorbic Acid in Treatment of Vitamin C Deficiencies. Arch Int Med., 75:407, 1945.
  • Dalldorf, G.: Vitamin C in Health and Disease. W.B. Saunders, 1945.
  • Musser, J.H.: Nutrition in the Aged. W.B. Saunders Co., 1945.

Page 36, Burns:

  • Knisely, M.H. et al: Arch Surg, 51:220, 1945
  • Knisely, M.H.: Science, 106:431, 1947.
  • Berkeley, W.T., Jr.: So Med J., 58:1182-1184.
  • Lund & Levenson: Arch Surg., 55:557,1947.
  • Bergman, H.C. et al: Am Hrt J., 29:506-512, 1945.
  • Lam, C.R.: Col Rev Surg Gyn & Obst., 72:390-400, 1941.
  • Klasson, D.H.: NY J Med., 51:2388-2392, Oct, 1951.

Page 37, Surgery, Shock;

  • Chambers, R. & Pollock, J.: J Gen Physiol, 10:739, 1927
  • Clark & Rassiter: Q J Exp Physiol., 32:279, 1944.
  • Barlett, M.K. et al: NEJM, 226:474, 1942.
  • Laninan, T.H. & Ingalls, TB.: Am Surg., 105:616, 1937.
  • Schumacher: Ohio State Med J., 42:1248, 1946.

Page 41-42, Poisonous Insects and Reptiles:

  • Klenner, F.R.: Hunting and Fishing Magazine, April, 1950.

Pages 43-54, Myasthenia Gravis and Multiple Sclerosis:

  • Klenner, F.R.: Response of Peripheral and Central Nerve Pathology to Megadoses of the Vitamin B Complex and other Metabolites. J Appl Nutrit., 25:#304, 1973.
  • Klenner, F.R.: Multiple Sclerosis Diagnosis and Treatment Suggestions. Original paper, unpublished.
  • Klenner, F.R.: Fatigue—Normal and Pathological with Special Consideration of Myasthenia Gravis and Multiple Sclerosis. So Med & Surg., 111:#9, Sept 1949.

Page 45:

  • Stern, E. I.: The Intraspinal Injection of Vitamin B1 for the Relief of Intractable Pain, and for Inflammatory and Degenerative Diseases of the Central Nervous System. Am J Surg., 34:495, 1938.
  • Rosenberg, L.E.: Vitamin Deficiency Diseases and the Vitamin Dependent Diseases with Reference to B and D., National Health Federation Bulletin Vol XVIII. #10, Nov 1972.
  • Moore, M.T.; Treatment of Multiple Sclerosis with Nicotinic Acid and Vitamin B1. Arch Int Med., 65:18, Jan 1940.

Other supportive articles from the medical literature:

  • Kempe, C.H.: A Key to the Secret of M.S., Med World News, July 7, 1972.
  • Schandl, D.K.: Dissertation on Environmental and Pyridoxine cause of M.S., The Charlotte Observer, Charlotte, N.C., April 23, 1973.
  • Brickner, R.M.: A Critique of Therapy in M.S., Bull Nue Inst NY., 4:665, April 19367.
  • Zimmerman, H.H. and Burack, E.: Lesions of the Nervous System Resulting from a Deficiency of the Vitamin B complex. Arch Path., 13:207, Feb 1932.
  • Spies, T.D. et al: The Use of Nicotinic Acid in the Treatment of Pellagra. JAMA, 110:622, Feb 1938.
  • Spies, T.D. and Aring, C.D.: The Effect of Vitamin B1 on the Peripheral Neuritis of Pellagra, JAMA, 110:1081, April, 1938.

Page 55, Toxic Doses:

  • Patterson, J.W.: J Biol Chem., 81-88, 1950.
  • Lambden, M.P. et al: Proc Soc Exp Biol Med., 85:190-192, 1954.

Need for Vitamin C:

  • Sabin: J Exp Med., 89:507-515, 1939.
  • Wright: Ann Int Med., 12, 4:516-528, Oct 1938.
  • Brody, H.D.: J Am Diet Assn., 29:588, 1953.
  • Regnier, E.: Rev of Allergy, 22:948, Oct 1968.


Adapted from Vitamin C as a Fundamental Medicine: Abstracts of Dr. Frederick R. Klenner, M.D.’s Published and Unpublished Work,
ISBN 0-943685-13-3, first printing 1988.
Page references apply to original publication.
HTML Revised .
Corrections and formatting © 2004 AscorbateWeb

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