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Fungalbioics Mycotoxins, Fungi, and Cancer

DEFINITION OF FUNGALBIONICS

The term FUNGALBIONICS was created in an attempt to describe one of the most dynamic microbial chemical factories ever encountered in the history of scientific exploration: the fungus

Fungi are masters at producing a wide array of biologically active substances which serve the producing fungus extremely well. These biological metabolites are anti-predatory, i.e. territory-protective, and exist to ensure that the fungus will survive as long as possible in this quite hostile world.

These metabolites are anti-viral, anti-bacterial. anti-protozoan, anti-insect, anti-animal and, of course, anti-human. These metabolites are referred to as mycotoxins. The term is derived from the Greek mykes, meaning fungus, and toxicum, meaning toxin or poison.

Mycotoxins Are Poisons.

One could test the validity of this most biologically potent fungal reality by eating a cupful of poison mushrooms, a species of fungus. However, it would be less fatal to simply read about the deadly effect which they have on humans and all other animals. For that mushroom, the name of the game is food, for in nature the animal which nibbles on them dies and is slowly consumed by the (root-like) mycelia under the ground which grow up into the hapless and dead creature. Many plants meet this same fate.

Thus, the term FUNGALBIONICS attempts to convey this remarkable degree of biological activity which these simple single-celled fungi demonstrate. All fungi are so empowered, some less against humans, some more so. While fungi are potentially our enemies, some of their mycotoxins, such as penicillin, have proven to be beneficial to humans who suffer from bacterial infections or other diseases.

The "bionic" nature of fungi is seen by the magnificent power to save human lives from bacterial infection which penicillin has demonstrated. That is indeed a bionic miracle. Other fungal-derived drugs are just as miraculous, as will be described later.

This series of FUNGALBIONICS books provide documentary evidence that fungi and their biological metabolites, the mycotoxins, are silent and relentless attackers of human health in that they cause the major "degenerative" and "cancerous" diseases which plague mankind.

FUNGALBIONICS appears to be a most appropriate term to describe the fungal/mycotoxin findings which will be presented in the following pages. lt is a term which the the physician author and his research associates have found to be acceptable. We hope that the reader will agree with us.

WHAT ARE FUNGI?

Fungi are single celled living forms of life which inhabit the land, air and waters of the earth. They are everywhere. They are more highly developed than the bacteria and viruses, and there are many more species among the fungi than are found among the other microbes. lt is estimated that there are over 500,000 different species.

Fungi have existed on earth hundreds of millions of years and, quite remarkably, have experienced little genetic change during that period of time. They are survivalists. Viable fungi can grow from spores which have been dormant for thousands of years, such as has been observed in spores which were found in Egyptian tombs.

Single fungal cells can only be seen under the microscope, but a colony of these cells makes a visible presence in the form of mushrooms, toad stools and molds on food or elsewhere. While plants, animals and humans are alive and well, the fungi around them are unable to overcome the natural defense mechanisms which higher forms of life possess. Once death of the living organism has occurred, however, the fungi become the principle undertakers and managers. They reduce all that has every lived into the molecules from which they were assembled. Biologists call this the carbon cycle, while Christians describe it as „dust to dust".

Unfortunately, though, there is one exception to this simple balanced equation of life and death and that is that the fungi can also attack the living while they are alive. At its most simplistic perspective, one has many fungi entering the intestinal tract, the nose and lungs, and organs exposed to the outside world. Though we generally do not develop an infection from such intrusions, some persons might contract a fungal infection such as "athlete's foot" or "ring worm" on the skin.

At the opposite extreme is the patient with AIDS who faces major life-threatening fungal infections because the immune system has lost its ability to protect the body from organisms which invade the body, such as fungi. In between these extremes are fungal infections associated with diseases such as diabetes, cancer as well as conditions which include cross infections amongst humans. Fortunately, though, the average person does not succumb to a serious fungal infection and the average life expectancy extends into the 70's.

All humans are colonized by Candida albicans and normal healthy persons do not die from this organism. This organism plays a very little role in causing human diseases.

(The concept that Candida causes many diseases is NOT a part of Fungalbionics nor is it supported by the extensive medical literature relative to Candida.

WHAT ARE MYCOTOXINS?

All physicians are familiar with fungal infections and the drugs used to treat them. With the exception of poisonous mushrooms, which are deadly to those foolish enough to eat them, few physicians are aware of the fact that fungi make toxins.

MYCOTOXINS-FRIENDS?... OR ENEMIES?... THEY ARE BOTH...

AS ENEMIES

As many as 1,000 compounds, classifiable as mycotoxins, were studied by the pharmacology industry as potential antibiotics in the 1930s and 1940s only to be discarded as being too toxic for higher life forms to be of value in treating bacterial diseases in humans. Little, if any of the discarded data was published. Yet what these toxicity studies actually documented was the existence of a large number of fungal-derived toxins which caused serious target organ injury in various animal models. Obviously, in retrospect, what was being seen was the pathology produced by the mycotoxins. In order to understand this toxicity, one only has to look at what some of these mycotoxins, used as medications, causes in humans:

The mycotoxin cyclosporin used for Transplantation causes cancer and atherosclerosis, complete with hyperlipidemia, in ALL humans who have received it. Many others develop gout and other diseases.

AS FRIENDS

However, to place the matter in proper perspective, the study of such fungal metabolites gave us penicillin at the beginning, quite later on cyclosporin, the most potent immunosuppressant Transplantation drug, lovastatin, and the other statins which have revolutionized the treatment of hyperlipidemia and atherosclerosis. The latter group is quite interesting in that they were initially developed as antifungal agents which just happened to have an effect in lowering blood levels of low density lipoproteins (commonly referred to as "bad cholesterol").

The members of this group of drugs are joined by another antifungal antibiotic, griseofulvin, which is also a remarkably efficient anti-atherosclerosis drug. All of this goes a long way to confirm the fungal etiology of atherosclerosis. This appears to be a quite valid conclusion since all of the other effective anticholesterol and/or anti-atherosclerotic therapeutic modalities share nothing in common except that they possess antifungal and/or antimycotoxin activity.

DISEASES RESPONDING TO ANTIFUNGAL DRUGS

The Fungalbionic Series of Books present data documenting the fungal/mycotoxin cause of a number of diseases. Equally important, the series also documents that each and every dietary measure or drug found to be effective in treating these diseases share nothing in common except that they are all antifungal and/ or antimycotoxic.

The importance of this therapeutic responsiveness should not be underestimated. If a cause of a disease is a microbe, it must respond to an appropriately selected antimicrobial agent.

In addition, diseases of unknown etiology which respond to antifungal-effective drugs suggest the probability that they have a fungal origin, particularly when there is no other proven explanation as to how the drug is working. Table 1 provides a number of human diseases which so respond and suggest a fungal/mycotoxin origin.


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